Methylcobalamin + ALA + Myo-Inositol + Benfotiamine + P-5-P + L-Methylfolate + Chromium Tablets

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Therapeutic Indication

Diabetic neuropathy & peripheral neuropathy
Oxidative stress & antioxidant support
Vitamin B-complex deficiency
Metabolic syndrome & insulin resistance
Cardiovascular health & endothelial function
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Methylcobalamin + ALA + Myo-Inositol + Benfotiamine + P-5-P + L-Methylfolate + Chromium

Tablet

Our composition contains Methylcobalamin which is better absorbed and retained than other forms of B12 (such as cyanocobalamin). Methylcobalamin protects nerve tissue and brain cells and promotes better sleep. Methylcobalamin is a cofactor of methionine synthase, which reduces toxic homocysteine to the essential amino acid methionine. Methylcobalamin also protects eye function against toxicity caused by excess glutamate.
L-Methylfolate is involved in neurotransmitter synthesis and critical enzyme reactions throughout the body. By depleting excess homocysteine folate benefits cardiovascular health and nervous system function.
Pyridoxal -5-phosphate plays a role in the synthesis of nucleic acids RNA and DNA, aids in the maintenance of the sodium-potassium balance, promotes red cell formation and provides nutritional support to the nervous system.

Speciality Neurology | Endocrinology | Cardiology | General Medicine
Tags Neuro Support | Antioxidant | Metabolic Health | Diabetes Care
Strength
  • Alpha Lipoic Acid 200 mg
  • Benfotiamine 150 mg
  • Myo-Inositol 150 mg
  • Pyridoxal-5-Phosphate 2 mg
  • L-Methylfolate 0.8 mcg
  • Methylcobalamin 1500 mcg
  • Chromium Picolinate 200 mcg
Packing Size
  • 10 Tablets

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Mechanism

  • Methylcobalamin: Supports nerve regeneration, DNA synthesis, and myelin sheath repair.
  • Alpha Lipoic Acid: Potent antioxidant, reduces oxidative stress, improves insulin sensitivity.
  • Myo-Inositol: Regulates insulin signaling, supports ovarian and metabolic health.
  • Benfotiamine: Lipid-soluble Vitamin B1 derivative, prevents advanced glycation end-products (AGEs) in diabetes.
  • Pyridoxal-5-Phosphate: Active Vitamin B6 coenzyme, essential for neurotransmitter synthesis and hemoglobin production.
  • L-Methylfolate: Active folate form, reduces homocysteine, supports neurotransmitter synthesis and vascular health.
  • Chromium Picolinate: Enhances insulin action, improves glucose metabolism.

Pharmacokinetics

  • Absorption: Rapid intestinal absorption; fat-soluble components absorbed with dietary fat.
  • Distribution: B-vitamins widely distributed; ALA and Chromium reach metabolic tissues.
  • Metabolism: Primarily hepatic metabolism; active forms bypass conversion steps.
  • Elimination: Renal excretion for vitamins and minerals; biliary for fat-soluble components.

Side Effects

  • Headache, dizziness
  • Nausea, vomiting, abdominal discomfort
  • Allergic reactions (rash, itching)
  • Mild gastrointestinal upset

Contraindication

  • Hypersensitivity to any component
  • Severe renal or hepatic impairment
  • Pregnancy & breastfeeding (unless prescribed)

Interaction

  • Methylcobalamin: May interact with omeprazole, colchicine, and chlorambucil, reducing absorption or efficacy.
  • Alpha Lipoic Acid: Enhances insulin sensitivity; caution with antidiabetic drugs (risk of hypoglycemia). May interact with thyroid medications.
  • Myo-Inositol: Generally safe, but may potentiate effects of insulin-sensitizing agents.
  • Benfotiamine: May reduce efficacy of certain chemotherapy agents; interacts with alcohol (reduces absorption).
  • Pyridoxal-5-Phosphate: Can reduce efficacy of levodopa unless combined with carbidopa; interacts with aspirin, anticoagulants (warfarin, heparin), antiplatelets (clopidogrel), and NSAIDs.
  • L-Methylfolate: May interact with anticonvulsants (phenytoin, carbamazepine) and warfarin; caution in psychiatric medications (risk of mood changes).
  • Chromium Picolinate: Potentiates insulin and oral hypoglycemics; may interact with corticosteroids and antacids.

Warning and Precautions

  • Use under medical supervision, especially in patients with diabetes, neuropathy, or cardiovascular disease.
  • Monitor blood glucose levels regularly when combined with antidiabetic therapy.
  • Check vitamin B12, folate, and chromium levels during long-term use.
  • Use cautiously in patients with clotting disorders or those on anticoagulant therapy (due to Vitamin B6 and folate interactions).
  • Pregnant and breastfeeding women should use only if prescribed by a physician.
  • Discontinue immediately if severe allergic reaction occurs.
  • Store below 30°C in a cool, dry place; protect from light and moisture.
  • Keep out of reach of children.

Dosage

As directed by the Dietician.